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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
Zearalenone (CAS 17924-92-4) is a mycotoxin produced primarily by Fusarium fungi frequently contaminating feed and food products It exhibits estrogenic activity through interaction with estrogen receptors thus altering endocrine signaling pathways Although acutely low in toxicity zearalenone effectively modulates estrogen receptor-mediated responses influencing hormonal balance in livestock species such as pigs cattle and sheep In biomedical research zearalenone serves as a tool compound to study estrogen receptor-mediated mechanisms and endocrine disruption particularly in young animals within veterinary pharmacological contexts
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Chemical. CAS 17924-92-4. Formula C18H22O5. MW 318.4. Isolated from Fusarium graminearum. Resorcylic acid lactone. Mycotoxin. Regulator of fungal morphogenesis. Mycoestrogen with anabolic and uterotrophic activity. Ecdysteroid antagonist. Gonadotropin inhibitor. Interleukin antagonist. Apoptosis inducer. Analytical standard in food industry.
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Zearalenone is a resorcylic acid lactone mycotoxin produced by Fusarium species, supplied as an analytical standard for research into estrogenic activity and mycotoxin contamination. The material is provided as a measured solid and is accompanied by supporting documentation for research and analytical use.
High purity (98.85%) suitable for analytical applications.
Molecular formula C18H22O5 and molecular weight 318.36.
Provided as a 50 mg solid; other pack sizes and a 10 mM DMSO solution are available.
Includes certificate of analysis and safety data sheet for traceability.
Intended for research and analytical testing of mycotoxin contamination and estrogenic effects.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Zearalenone is a nonsteroidal estrogenic mycotoxin provided as an analytical standard for research and analytical applications, including method development, calibration, and mycotoxin screening.
Zearalenone (CAS 17924-92-4) is a mycotoxin produced primarily by Fusarium fungi frequently contaminating feed and food products It exhibits estrogenic activity through interaction with estrogen receptors thus altering endocrine signaling pathways Although acutely low in toxicity zearalenone effectively modulates estrogen receptor-mediated responses influencing hormonal balance in livestock species such as pigs cattle and sheep In biomedical research zearalenone serves as a tool compound to study estrogen receptor-mediated mechanisms and endocrine disruption particularly in young animals within veterinary pharmacological contexts
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Epothilone A (CAS 152044-53-6) is a natural macrolide compound originally isolated from the myxobacterium Sorangium cellulosum It exerts its biological activity by stabilizing microtubules thereby disrupting microtubule dynamics required for cell division In vitro Epothilone A exhibits potent cytotoxicity against human cancer cell lines with an IC50 of 4 4 nM in HCT-116 colorectal carcinoma cells In SKOV-3 ovarian cancer cells the reported IC50 is 20 4 1 4 nM and antiproliferative activity surpasses that of paclitaxel in prolonged exposure assays Epothilone A research applications include elucidating mechanisms of microtubule stabilization and investigating antitumor effects in preclinical cancer models
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MW 507.7 Da, Purity >98%. Microtubule-stabilizing agent. Analog of Epothilone A and D (ab143615 and ab143616). Displays highest efficacy in class III β-tubulin overexpressing malignancies. Inhibits Paclitaxel (ab120143)-resistant cell lines. Shows antitumor effects in vivo. Orally active.
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
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Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More